- Targets the enzyme PDE5, which interrupts the natural arousal response
- 1 tablet, taken at least 30 minutes before sex
- Effects can last up to 36 hours
Sexual Health
Tadalafil
Tadalafil is a prescription treatment for erectile dysfunction, working in the same way as Sildenafil by blocking the enzyme PDE5 to restore blood flow when aroused. The key difference is that the effects can last up to 36 hours, giving more flexibility for spontaneous sex.
Your clinician confirms the right strength for you.
Select your dose to see your options
Pay per order, order again only when you need it. Delivery included.
- Reviewed by a UK-registered clinician before anything is dispatched
- Refunded in full if a clinician decides treatment isn't right for you
- Discreet, tracked delivery
What's included with every order
Complete care is standard with every order:
- Discreet, tracked delivery included and in plain packaging
- A named UK clinician reviews and prescribes every order
- Treatment decisions typically arrive the same day
- Monthly clinician check-ins to manage dose changes
- Message your care team in between check-ins
- Support with nutrition, exercise and sleep
- First order refunded in full if a clinician decides treatment isn't right for you
- Pay per order, order again only when you need it.
Delivery & packaging
Plain packaging, tracked to your door, and temperature-controlled where treatment needs it. Nothing on the outside says what's inside. Depending on where you live, we use DPD or Royal Mail tracked delivery. Our priority is getting your medication to you quickly and safely.
Refunds & stopping
If a clinician decides treatment isn't right for you, you're refunded in full.
Tadalafil at Curate, in four facts.
- Up to 36 hoursone as-needed dose stays active
- Daily optiona low dose each day, nothing to time
- Named prescribersGPhC-registered, verifiable on the register
- From £19.99a month's worth, delivery included, no lock-in
Transparent pricing
Simple, honest pricing.
You pay per order, buy a single lot or stock up on one, two or three months' worth at a time. Every price includes delivery. If a clinician decides treatment isn't right for you, you're refunded in full.
Tadalafil is available as a daily dose or taken as needed. Your clinician confirms the right approach for you.
| Strength | 1 month's worth | 2 months' worth | 3 months' worth |
|---|---|---|---|
| 10mg | £19.99 | £39.98 | £59.97 |
| 20mg | £19.99 | £39.98 | £59.97 |
Dosing
As-needed or daily, your choice.
Tadalafil suits two routines: a low daily dose so you are always ready, or a stronger as-needed dose taken before sex. Your clinician helps you choose and adjust.
5 mg
A low dose taken daily, so spontaneity is back on the table and there is nothing to plan around the moment.
Take no more than one dose in any 24 hours, and do not mix the daily and as-needed routines. Your clinician sets the approach that fits your life and reviews it with you.
How it works in the body
Blood flow, on your schedule.
Tadalafil is the active ingredient in Cialis, known for how long it lasts. Like all ED tablets, it works with arousal, not instead of it. Select a step to see how.
Mechanism per the tadalafil SmPC. Tadalafil is a long-acting PDE5 inhibitor.
What to expect
What it looks like, without the pressure.
ED treatment is rarely about one perfect first try. Here is what the journey usually looks like as you find what suits you.
A test run, not a verdict
The first dose tells you how your body responds. Nerves and timing can blunt it, so treat it as information rather than a final answer.
Tadalafil is effective for the majority of men with erectile dysfunction. Individual response varies and is reviewed by your clinician.
Side effects
What is normal, and what is not.
Most side effects are mild and short-lived, linked to the way tadalafil widens blood vessels. Knowing what is expected, and what is not, keeps you confident.
Common, and usually settle
- Headache, especially the first few times
- Indigestion or an upset stomach
- Back pain or muscle aches, which tend to settle in a day or two
- Facial flushing or feeling warm
- A stuffy or blocked nose
Speak to a clinician if you notice
- An erection lasting more than four hours, which needs urgent care
- Chest pain, especially during or after sex
- Sudden loss of vision or hearing
- An allergic reaction: swelling, rash, or trouble breathing
- Side effects that are severe or do not settle
Tadalafil should never be taken with nitrate heart medicines. Your clinician checks this and your wider health before prescribing, and is a message away whenever you need them.
How to use it
Easier than you think.
Tadalafil fits around you. Take a low dose every day, or a stronger dose before sex, whichever your clinician recommends.
Nervous about the first one? Any questions and you can speak to our clinical team.
Your clinical team
You've made this first step, and that's often the hardest. It's a sensitive subject, and our clinicians are here to treat you with discretion and respect. By understanding your health profile and the root cause of your symptoms, we can prescribe the most suitable treatment for you.
Every prescription is decided by a named, UK-registered pharmacist prescriber, and the same team reviews your progress at each step. You can verify any of them on the GPhC register.
Patient reviews
17,000+ reviews. Every one from a real patient.
One of the largest review bases in UK online healthcare, these are recent five-star reviews, word for word.
Good to know
Questions, answered honestly.
If anything here doesn't cover it, our care team is one message away, in complete confidence.
Still have questions? Message the care team
What is tadalafil?
Tadalafil (also known as Cialis) is an MHRA-approved medication for erectile dysfunction. It increases blood flow to the penis during sexual stimulation.
Are there different doses?
Tadalafil comes in 5mg (daily), 10mg and 20mg tablets. Once you complete your online consultation, our clinicians will prescribe the most appropriate dose for you.
When do I take it, as needed or daily?
Take tadalafil about 30 minutes before sexual intercourse. The 10mg and 20mg tablets are taken when required, while the 5mg tablet is taken daily at the same time each day and allows for spontaneous erections.
How long do the effects last?
Tadalafil can last for up to 36 hours, which is the main difference from sildenafil. Taken daily, the 5mg dose builds up in your system over time.
What are the side effects?
Tadalafil is usually well tolerated. The most common side effects are facial flushing, headaches, indigestion, nasal congestion and dizziness, which are usually mild and temporary. Rare but serious effects such as an erection lasting longer than 4 hours need urgent medical attention.
Can I drink alcohol while taking it?
Moderate alcohol (maximum 2 units) is generally considered safe, but both alcohol and tadalafil lower blood pressure, so combining them can cause dizziness or fainting. Alcohol can also affect performance.
Refer a friend. £40 for them, £40 for you.
Your referral link automatically gives them £40off their first month’s order. Once your friend's first order is delivered, a £40 credit will appear in Your Rewards and can be used towards your next treatment order.
Advice & guides
Knowledge that keeps you going.
Tadalafil side effects: what to expect and what to watch for
Headache, flushing, indigestion and back pain lead the list. Why tadalafil's long duration changes the side-effect picture, and the signs that need urgent care.
Can you buy sildenafil over the counter in the UK?
Standard sildenafil needs a prescription in the UK, but a 50mg pharmacy version can be supplied after a pharmacist consultation. How the routes differ and how to stay safe.
Can women take sildenafil?
Sildenafil is licensed in the UK for erectile dysfunction in men, not for sexual problems in women. What the research found, why the biology differs, and what actually helps.
Your move
The most difficult part is starting.
The rest, we support you through.
You've made this first step, and that's often the hardest. It's a sensitive subject, and our clinicians are here to treat you with discretion and respect. By understanding your health profile and the root cause of your symptoms, we can prescribe the most suitable treatment for you.
Start Consultation