- Strengths
- 10mg or 20mg
- How it's taken
- Before sex, up to 36 hours of effect
- Suits
- Occasional use
- Price at Curate
- From £19.99 a month
Sexual Health at Curate
Cialis and tadalafil, explained.
Cialis is the brand name for tadalafil — the erectile dysfunction treatment known for lasting up to 36 hours. The generic version contains the same active ingredient at a much lower price, prescribed online by named UK clinicians.
- UK-registered clinicians
- GPhC-registered pharmacy
- CQC-regulated service

Cialis and tadalafil — what's the difference?
Nothing clinical. Cialis is the original branded tadalafil; since the patent expired, other licensed manufacturers make the same active ingredient as generic tadalafil, licensed by the MHRA to the same standards. The difference is price.
Tadalafil works like sildenafil — blocking the enzyme PDE5 to restore blood flow when aroused — but stays active far longer: up to 36 hours, which is why it's sometimes called the weekend pill. It's also available as a low daily dose, so spontaneity doesn't depend on timing a tablet.
Compare
Your options
- Strengths
- 5mg
- How it's taken
- One tablet every day
- Suits
- Regular sex life, no planning
- Price at Curate
- From £34.99 a month
Your clinician confirms the right strength and approach for you.
Transparent pricing
Tadalafil price at Curate
A one-off price, not a subscription. Buy a single lot or stock up — one, two or three months' worth at a time. You pay when you order; if a clinician decides treatment isn't right for you, you're refunded in full.
Tadalafil is available as a daily dose or taken as needed. Your clinician confirms the right approach for you.
| Strength | 1 month's worth | 2 months' worth | 3 months' worth |
|---|---|---|---|
| 5mg daily | £34.99 | £69.98 | £104.97 |
| 10mg | £19.99 | £39.98 | £59.97 |
| 20mg | £19.99 | £39.98 | £59.97 |
How prescribing works
Tadalafil is a prescription-only medicine: it interacts with some medicines and conditions — particularly nitrates — so a clinical check comes first. At Curate that's a confidential online assessment reviewed by a named UK clinician, with discreet delivery and follow-up built in.
Read the full treatment page: tadalafil at Curate. Prefer the shorter-acting option? See
sildenafil — the active ingredient in Viagra.
It's common, and it's treatable
A confidential consultation with no waiting room. Reviewed by a named UK clinician, delivered discreetly.
Questions
Cialis and tadalafil, answered.
Is generic tadalafil as good as Cialis?
It contains the same active ingredient at the same strengths, and generic medicines are licensed by the MHRA to the same standards of quality and performance as the branded original. The main practical difference is price.
How long does tadalafil last?
The as-needed doses (10mg and 20mg) can remain active for up to 36 hours — it doesn't mean a 36-hour erection, but that the medicine can work with arousal during that window. The 5mg daily dose keeps a steady level in your system all the time.
Tadalafil or sildenafil — which should I choose?
They work the same way; the practical differences are duration and dosing pattern. Tadalafil lasts up to 36 hours and has a daily option; sildenafil works within the hour and lasts around four. Your clinician helps you choose based on your health profile and how you'd use it.
Do I need a prescription for Cialis in the UK?
Yes — tadalafil in all its forms is prescription-only in the UK. At Curate that means a confidential online assessment reviewed by a named UK clinician before anything is dispensed.
Explore treatments and guides
Advice & guides
Knowledge that keeps you going.

Can you buy sildenafil over the counter in the UK?
Standard sildenafil needs a prescription in the UK, but a 50mg pharmacy version can be supplied after a pharmacist consultation. How the routes differ and how to stay safe.

Can women take sildenafil?
Sildenafil is licensed in the UK for erectile dysfunction in men, not for sexual problems in women. What the research found, why the biology differs, and what actually helps.

How long does sildenafil take to work?
Sildenafil typically works within 30 to 60 minutes, but food, timing and technique change everything. How to give the tablet its best chance.